IPHD Lab
Chungbuk National University
Understanding immune mechanisms in human diseases through cutting-edge epigenomic approaches and collaborative research excellence.
Learn MoreChungbuk National University
Understanding immune mechanisms in human diseases through cutting-edge epigenomic approaches and collaborative research excellence.
Learn MoreUnderstanding immune mechanisms in human diseases
The Immune Profiling in Human Diseases (IPHD) Laboratory, led by Dr. Kyuho Kang, focuses on understanding the complex interplay between immune responses and various human diseases. Our research applies cutting-edge epigenomic approaches to investigate immune cell functions in the context of cancer and chronic inflammatory conditions.
We utilize advanced genomic and epigenomic technologies to profile immune cells and understand how their functions are dysregulated in disease states. Our work has significant implications for the development of novel therapeutic strategies for cancer and inflammatory disorders.
Located at Chungbuk National University's Department of Biology, our team collaborates with clinicians and researchers globally to translate fundamental discoveries into clinical applications.
Single-cell genomics, epigenomics, and multiomics approaches
International partnerships for translational research
Translating discoveries into therapeutic applications
Our key areas of investigation
We apply cutting-edge techniques including ChIP-seq, ATAC-seq, CUT&Tag, RNA-seq, and single-cell multi-omics to map the epigenetic landscapes of immune cells in health and disease.
We investigate the epigenetic and transcriptional regulation of macrophage activation and polarization in response to cytokines and environmental signals, with special focus on interferon and JAK-STAT signaling pathways.
Our research explores how tumor-associated macrophages and other immune cells are regulated in the cancer microenvironment, focusing on epigenetic reprogramming that drives cancer progression.
We study the underlying mechanisms of chronic inflammatory conditions, including rheumatoid arthritis and chronic rhinosinusitis, to identify novel therapeutic targets.
Our lab works on identifying and validating biomarkers for disease diagnosis, prognosis, and treatment response, with patents for bladder cancer prognostic markers.
We develop and apply bioinformatic approaches to integrate multi-omics data for uncovering novel biological insights and potential therapeutic targets.
Associate Professor
Department of Biology, College of Natural Sciences
Chungbuk National University
Education:
Ph.D. Immunology & Microbial Pathogenesis, Cornell University (2016)
M.S. Life Science, GIST (2006)
B.S. Life Science, Sogang University (2004)
Selected recent publications from our laboratory
Advanced Science (2026) Jan 7:e10302 (5 Year IF = 15.6)
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STAR Protocols (2025) Nov 27;6(4):104238
Experimental & Molecular Medicine (2025) 07 April 2025 (5 Year IF = 14.2)
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iScience (2025)
Cell Death & Disease (2024) Nov 8;15(11):801 (5 Year IF = 9.8)
Nature Communications (2019) July 25;10(1):3320
Google Scholar: Cited by 148
Immunity (2017) Aug 15;47(2):235-250
Google Scholar: Cited by 225
Cell Reports (2016) Sep 20;16(12):3121-9
Google Scholar: Cited by 91
Meet our dedicated research team
Principal Investigator
Associate Professor
Postdoctoral Researcher
Cancer Epigenomics
Ph.D. Student
Inflammatory Disease Research
Ph.D. Student
Cancer Biology
Ph.D. Student
Cancer Epigenomics
Ph.D. Student
Cytokine Signaling
M.S. Student
Type 2 Inflammation
Undergraduate Student
Cancer Immunology
Postdoctoral Researcher
Samsung Medical Center, Institute for Future Medicine
Get in touch with our research team
Institution
Department of Biology, College of Natural Sciences
Chungbuk National University
We welcome motivated students and researchers interested in immunology, epigenetics, and computational biology. Please contact us to discuss potential opportunities.
Please note: We are not recruiting international students this year.